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Re: my exp is waiting is only relevant to s/e's » iforgotmypassword

Posted by SLS on June 26, 2012, at 5:42:28

In reply to my exp is waiting is only relevant to s/e's » SLS, posted by iforgotmypassword on June 26, 2012, at 1:20:30

> we may not be after the same mechanism tho. but, given the mention of parnate i think i saw before... it would work well with it and it's metabolites i think, and having mao-b smushed might help allay some worry about the oxidative potential of DA.

> an odd thing is my experience is that lamotrigine helps fight side effect with memantine increases. i think this is because memantine redirects glutamate to other receptors (AMPA, kainate..).

Wow. You really know your stuff. There is a secondary effect of memantine on AMPA and kainate receptors via NMDA receptors, but it is complex, and I don't understand it.

When I began memantine treatment at 20 mg, I immediately developed cognitive blunting. My doctor asked that I try Topamax instead at this juncture. If Topamax does not yield results, I might retry memantine, but starting at 5 mg.

Thanks for your input.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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