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Re: getting frustrated - Parnate experts? » g_g_g_unit

Posted by SLS on March 18, 2012, at 13:56:41

In reply to getting frustrated - Parnate experts?, posted by g_g_g_unit on March 18, 2012, at 8:27:59

I agree with Lou Pilder that clonidine isn't the best drug to experiment with when taking an MAOI. I don't like it for two reasons:

1. Hypotension. Clonidine might work synergistically with MAOIs to reduce blood pressure and produce an unacceptable degree of dizziness. This probably would not occur until you reach higher dosages of Parnate, though. Having said that, I can report that adding prazosin, another sympatholytic antihypertensive drug, to Parnate 80 mg has not produced very much more dizziness than the Parnate would produce alone. I experienced significant dizziness during the first week or two, but it subsided. Perhaps the same thing would occur with clonidine. It really is an experiment for which I cannot predict the outcome.

2. Depression. Clonidine is often depressogenic, even for people who don't have a mood disorder. Pharmacologically, clonidine is the antithesis of Remeron with respect to NE neurotransmission.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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