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Re: why do they say ketamine 'resets' the brain » poser938

Posted by SLS on March 17, 2012, at 5:28:57

In reply to why do they say ketamine 'resets' the brain, posted by poser938 on March 17, 2012, at 0:48:53

> that it is like what a windows boot up disc is to windows. i find it hard to make sense of some things i read lately, but could anyone else try and explain this?

Not really.

Ok.

Here's one attempt:

I don't know if ketamine "resets" the entire brain - probably not.

Perhaps ketamine "wakes up" certain dead circuits and/or "mutes" overactive ones. This recreates the healthy dynamics our genes originally coded for, at least temporarily. After this, gene activity might change, leading to a more persistent antidepressant effect. Ketamine treatment does produce an increase in BDNF.

- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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