Posted by SLS on March 1, 2012, at 4:44:09
In reply to Re: Toradol for migraine ? (on EMSAM), posted by ed_uk2010 on March 1, 2012, at 1:43:54
> There is little evidence of a major interaction between MAOIs and sumatriptan, apart from decreased metabolism of the sumatriptan.
I see that sumatriptan is a specific agonist of 5-HT1d receptors. No other serotonin receptors are affected. Do you know of any 5-HT agonists that are dangerous to combine with MAOIs? I take Abilify, which is a partial agonist at 5-HT1a receptors. I don't react badly when I combine it with Nardil or Parnate. Also, what is the function of 5-HT1d receptors other than modulating blood vascular tone? I understand that clinical observation takes precedence over feeble theories, but I am curious.
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1011999
URL: http://www.dr-bob.org/babble/20120221/msgs/1012084.html