Posted by SLS on May 1, 2011, at 5:11:14
In reply to Re: PLEASE READ.Pro/con:Gabapentin-agitated depression, posted by Christ_empowered on May 1, 2011, at 4:24:57
> If you like gabapentin, get that Lyrica script ASAP. Maybe you'll be able to get better results w/ less sedation? One thing I noticed about gabapentin...over time, it made me stupid. Since Lyrica is stronger, maybe you'll be able to get even better results w/o cognitive impairment
I agree. There is no guarantee, of course, but Lyrica also inhibits alpha2delta calcium channels in the same way as Neurontin.
> I wouldn't worry too much about addiction. Some people find gabapentin pleasant; that's really not a big deal. I mean, who said psychiatric treatment HAS to be an unpleasant experience? As long as you're keeping up with your program and able to function, keep poppin' the Neurontin (or Lyrica).
I agree - again. Judge the result and not the theory. Cognitive impairment is a possible side effect of both Neurontin and Lyrica. Since there are no long-term irreversible side effects reported for either drug, I would consider a trial with Lyrica if Neurontin has plateaued for you. The pharmacokinetics of the two drugs are very different. Lyrica gets into the brain to a greater extent.
http://www.ncbi.nlm.nih.gov/pubmed/20818832
Good luck.
- Scott
Some see things as they are and ask why.
I dream of things that never were and ask why not.
poster:SLS
thread:984211
URL: http://www.dr-bob.org/babble/20110418/msgs/984264.html