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Re: Inflammation + Treatment-Resistant Depression

Posted by desolationrower on March 30, 2011, at 12:16:00

In reply to Inflammation + Treatment-Resistant Depression, posted by jjjaspar on March 28, 2011, at 12:42:11

Yes, other anti-inflammatories have shown antidepressant effects:
aspirin
w-3 oil
celecoxib

most antidepressants show anti-inflammatory effects too.

bupropion lowers tnf-alpha specifically, like the mentioned drug.

philipa: direct inhibitors can increase infection risk: tnf-a and similar cytokines are part of the immune system's signal of an intruder, like infection or cancer. But if you aren't infected or don't have a tumor, you shouldn't have elevated levels. Chronic inflammation actually causes cancers, as well as depression, heart disease, etc.

same thing as adrenaline: good on occasion (helps run away from lion, or just exercise). bad if its always high.

-d/r


Better living through chemistry, socialism, and big phallic rockets (with a side of roquette)

 

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poster:desolationrower thread:981342
URL: http://www.dr-bob.org/babble/20110321/msgs/981465.html