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Re: Adding agomelatine to MAOI? » SLS

Posted by Dr. Fischer-Terworth on March 13, 2011, at 6:19:10

In reply to Adding agomelatine to MAOI?, posted by SLS on February 25, 2010, at 10:09:08


Hi,

I think it's possible. I am on tranylcypromine
40 mg for OCD and anxiety, very effective and
tolerable without diet, despite of insomnia.
As I developed Zolpidem tolerance after 6
years my psychiatrist suggested agomelatine
25 mg. It has good effects, I think kind of
mood stabilizing effects, and sleep has improved
at least moderately.
I tolerate the combination without andy side
effects. Maybe it's the same with the Phenelzine
also being an irreversible MAOI. Maybe it
reduces the Tranylcypromine's stimulating effect
a bit.
Serotonergic risks can be excluded because
agomelatine does not raise serotonin levels,
it justs blocks 5HT2c-receptors.

Hope this can be helpful.

Best wishes, Christian FT


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poster:Dr. Fischer-Terworth thread:937860
URL: http://www.dr-bob.org/babble/20110220/msgs/980416.html