Posted by Ron Hill on January 8, 2011, at 21:09:12
In reply to Nardil Follow-Up, posted by mantus on December 24, 2010, at 19:57:47
Mantus,
I've been on Nardil for about four years, and it is a tremendous antidepressant for me.
The appropriate dosage is 1 mg of Nardil/kg of body weight. Having said that, often patients end up taking 90 mg/day regardless of their body weight.
For me, Nardil did not kick-in fully until I increased to 90 mg/day. At 90 it kicked-in within a couple of weeks.
Please listen to me carefully about the side effects and how to minimize them. I say this because, in retrospect, I wish someone had told me these things before I started Nardil.
First, weight gain is the biggest issue. Therefore, I encourage you with all of my might to weight yourself everyday and DO NOT allow yourself to gain weight. Diet and exercise as much as it takes to keep from gaining weight. It is easier to keep the weight off than it is to lose it once the weight is packed on. Please, please do this, otherwise the weight gain can be huge.
I'd always been a thin person all of my life. As an adult I always weighted 177 lb at 5'11.5". An exception was when I was at my triathlon racing weight of 155 lb. Now that I am on Nardil I weigh 260 lbs and I hate it. Mantus, please keep the weight off right from the start.
Second, for the constipation, take a large dosage of a good magnesium chelation (not mg oxide). Keep raising the dosage until the constipation problem is resolved. Also, eat a lot of fiber.
As a male, due to Nardil I have lost my sex drive, I have erectile dysfunction, and I have very delayed orgasm, often to the point of anorgasmia. Viagra helps the ED.
You might wonder why in the world anyone would put up with these very difficult side effects. In my case, the answer is that Nardil is a necessary component in my med combo.
Lest I mislead you, Nardil did not resolve all of my psychiatric symptoms. For example, I continued to ultra rapid cycle even after my addition of Nardil. But, Nardil reduced the severity of the depressive phase of my ultra rapid cycling. It was only when I added Valdoxan that my ultra rapid cycling stopped and I became fully well. See my list of meds, vitamins, and supplements, below.
Nardil distroys B6, so take a good multi-vitamin:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1188621/And, I'm sure you know the diet restrictions.
-- Ron
dx: Bipolar II and mild OCPD
600 mg/day Trileptal (oxcarbazepine)
200 mg/day Lamictal (lamotrigine)
500 mg/day Keppra (levetiracetam)
90 mg/day Nardil (phenelzine)
12.5 mg at betime Valdoxan (agomelatine)
3.75 mg/day Deplin (taken with 2500 mcg/day of sublingual methyl B-12, and 12.5mg/day of sublingual P-5-P)
2.5 mg/day Adderal XR45 ml/day of Carlsons Bottled Fish Oil
100 mg/day phosphatidylserene
One Multi-vitamin/day; Only 100% of all the usual vitamins; Look for good chelations. NO VANADIUM!!
2000 IU/day Vitamin D-3
850 mg/day of Mg 212% of RDA (as 5 grams of Mg Malate)
200 mcg/day GTF Chromium
600 mcg/day Chromium Picolinate
200 mg/day Co-Q10
1000 mg/day Cinnamon
480 mg/day Milk Thistle
2 g Vitamin C
Whats next to add?:
NAC, + 8 to 10 glasses of water, + Acetyl-L-Carnitine, + Alpha-Lipoic Acid-----------------------------------
> Hello everybody,
>
> I wanted to follow up a bit on my Nardil experience. Basically, I haven't felt any difference for the positive and only maybe worse. I don't think it is the medicine making things worse, but I just wanted some input from people that might know more than me. I am struggling greatley right now, (everything seems daunting, crying daily, getting completely lost in my negative thinking and can't seem to get out, no desire to be around people or do anything, hopelessness, things are very, very badetc...) I do have some levels of anxiety, but alot of it is being masked by me taking 1.5mgs of ativan 3x/day in hopes that the nardil will kick in, but it doesn't seem to really do much other than help me make it through a normal day. I have been on 45mgs of nardil since 12/4 and really need some sign that this medicine is going to do something. I know plenty of people do not respond to 60mgs or more, but please give any support or advice you would have right now. please
poster:Ron Hill
thread:974555
URL: http://www.dr-bob.org/babble/20101231/msgs/976248.html