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Re: noone wants nmda antagonists anymore?

Posted by europerep on July 17, 2010, at 10:36:09

In reply to Re: noone wants nmda antagonists anymore? » europerep, posted by jade k on June 23, 2010, at 15:08:22

hey there,
just a small update, it seems the phase II trials have started at the beginning of this month:
http://behavioralhealthcentral.com/index.php/20100701228686/Pharma-News/evotec-starts-phase-ii-clinical-studies-in-treatment-resistant-depression.html

jade, I didn't see any answer to this thread before it disappeared, that's why I didn't reply..
it's basically just another antidepressant, but it's made specifically for treatment-resistant depression. that doesn't mean it can't be used for regular depression, but I find it "courageous" to market it as that, because this obviously means that it has to outperform regular antidepressants already in the clinical trials.
I am very very interested in the development of these drugs, since NMDA antagonists like ketamine do show significant efficacy in TRD patients.

 

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