Posted by tom2228 on June 27, 2010, at 15:20:25
In reply to Re: EMSAM. Would be great if only not for..., posted by Rosy Crucifiction on June 25, 2010, at 17:35:31
> Emsam doesn't convert to amphetamine since it isn't metabolized in the GI tract. It is stimulating, but you will get used to that in a few days. It can be a big help for anergic or atypical depressives.
Not true. The metabolism to l-amphetamine takes places in the liver actually. The difference with emsam as opposed to oral selegiline is that the patch, by bypassing first-pass metabolism, leads to the creation of LESS amphetamine metabolites. But regardless of route of administration, the drugs eventually go through the liver to be metabolized.
I got off the patch after day 4 and switched to Parnate because I can't agree that I would get used to the l-amp. I was on adderall for about half a year and the l-amp didn't let up too much for me. I actually find l-amphetamine to be sedating.. while at the same time making me feel cracked out. Tired and cracked out. I hate it lol.
But you're definitely right that it would be great for anergic/atypical depressives.. just not me. Vyvanse and dexedrine (pure d-amp) were so much better for me.. I just wouldn't be satisfied with emsam in the long run for this reason.
poster:tom2228
thread:951991
URL: http://www.dr-bob.org/babble/20100615/msgs/952398.html