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Re: Prozac + elavil - I need reassurance! » Brainbeard

Posted by orbital on January 4, 2010, at 15:26:56

In reply to Re: Prozac + elavil - I need reassurance!, posted by Brainbeard on January 4, 2010, at 14:36:59

I really appreciate your input Brainbeard, thank you very much!

I trust my doc 100%, I know she would never prescribe something unless she is absolutely sure that there's no risk involved. I would even say that's she's overly cautious (if there's such a thing), she's not big on of polypharmacy.

Still, I was a bit weary when I searched Babble for info on this combo, and found very few first hand accounts.

I'll be seeing my doc later this week, I'll discuss my options thoroughly with her then.

Thanks again! :)

> Lower dose Prozac with low dose Elavil (amitriptyline) is a fine combination.
>
> Here's a handy study to give you an idea of Prozac's potentiation of amitriptyline: http://www.ncbi.nlm.nih.gov/pubmed/7751409
>
> A regimen of 20mg of Prozac raises amitriptyline blood levels about twofold, but nortriptyline levels (the active metabolite) about ninefold.
>
> I'm on 25mg of amitriptyline at the moment, and I've been taking small doses of Prozac (about 5mg a day) for a while.
>
> Your doc has been perfectly cautious by setting the max at 25mg.


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