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Re: Effexor vs. Cymbalta for TRD? » jerrypharmstudent

Posted by SLS on November 16, 2009, at 17:07:13

In reply to Effexor vs. Cymbalta for TRD?, posted by jerrypharmstudent on November 16, 2009, at 16:29:57

> Hmm...so now I don't know weather to ask for Cymbalta or Effexor. Anyone know which has better efficacy for TRD?

I don't think there is any universal hierarchy of antidepressants arranged by efficacy to treat TRD. I have seen some people respond to Cymbalta whom did not respond to Effexor. For others, the reverse is true. One thing that is often suggested, though, is that polypharmacy is often the key to treating TRD successfully. A few doctors regularly combine antidepressants from different classes, hoping to produce a synergism to effect a treatment response. I was impressed by what I experienced using a combination of Effexor and nortriptyline. Combining any SSRI with a tricyclic is worth a try. Also, combining Wellbutrin with either Lexapro or Effexor seems to be particularly effective.


- Scott


 

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