Re: Buspirone vs Pindolol

Posted by SLS on September 1, 2009, at 10:53:41

In reply to Re: Buspirone vs Pindolol » tensor, posted by SLS on September 1, 2009, at 6:54:47

> > What are your experiences with these as augmentors in treating depression? Is one of them to prefer?
> >
> > /Mattias
>
>
> Buspirone has more potential to be effective as an augmenter of antidpressants. I guess you already know that buspirone and pindolol do opposite things at 5-HT1a receptors. Pindolol has been reported to speed-up the response to SRI drugs, but does not increase the response rate. Buspirone does. You need to take into consideration that buspirone has a major metabolite that acts as a NE alpha2 antagonist, a property shared with mirtazapine (Remeron). You get two drugs in one with buspirone.
It really is a crime that gepirone was not approved. It acts like buspirone, only without the dopamine receptor blockade.

- Scott

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Buspirone vs Pindolol tensor 9/1/09
Re: Buspirone vs Pindolol » tensor SLS 9/1/09
Re: Buspirone vs Pindolol SLS 9/1/09
Thank you (nm) » SLS tensor 9/1/09
Re: Buspirone vs Pindolol Brainbeard 9/1/09

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