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My history with MAOI's » SLS

Posted by AdamCanada2 on August 20, 2009, at 13:55:51

In reply to Re: 5mg Selegiline/Ensam too much/little?? Oral, posted by SLS on August 20, 2009, at 10:53:25

Parnate was tremendously promising when I tried it earlier in the year. Within the first day I felt an improvement. 10-25mg seemed to help a lot but huge insomnia developed. horrendous even. sometimes only 2-3 hours of sleep but i had so much energy that even with such poor sleep i was often able to half the time be in an energized state. evenings would be quite awful from exhaustion. but the overall mood benifits, motivation, drive, enjoyment, etc were nice. 30mg parnate though ruined it. It became a reversal of effects. Insomnia turned into oversleeping and tiredness. Mind was foggy. More depressed, little drive to do anything. Returning to lower doses didn't help at that point. Something happened with the medication and even down to 10mg it had the same sleepy tired effect of dreadfulness.

Nardil I forget the dose but it didn't help a too much. It deffinetly helped to a degree. Sure life was more enjoyable than not being on an anti-depressant but it never felt like I was anywhere near normal. I didn't want to settle for merely being slightly social and somewhat able to enjoy things.

And of course this Selegiline which was a beacon of hope during days 5-8. I started to remember how beautiful life could be.

Thanks for med suggestions

> > Please help in any way you can.
>
> I think it will be important to have patience when trying different treatments. It is the nature of the beast that antidepressants take a minimum of 2-4 weeks to produce an improvement. It is sometimes counterproductive to watch for daily or even hourly changes. The important thing is to establish a trend. Of course, if you can't tolerate the drug, that's a good reason to abort a trial.
>
> At the moment, I don't have any suggestions as to what direction to take your treatment. If you want, you can keep the selegiline, but add a SSRI or SNRI, and then supplement that with a drug like nortriptyline or desipramine. You could even go with a similar combination using Wellbutrin instead of a tricyclic.
>
> What has been your history regarding the use of MAOIs?
>
>
> - Scott


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poster:AdamCanada2 thread:912238
URL: http://www.dr-bob.org/babble/20090818/msgs/913164.html