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Re: Nortriptyline Bust » linkadge

Posted by SLS on July 27, 2009, at 16:31:09

In reply to Re: Nortriptyline Bust, posted by linkadge on July 27, 2009, at 15:54:21

> 1. Melancholic
> 2. Weight loss
> 3. Early morning awakenings
> 4. Worse in the mornings
> 5. Male
> 6. First degree relative responding to TCA
> 7. Areactive
> 8. Psychomotor retardation
> 9. Agitation
>
> Well yes, actually every single one of those appplies. I still do intend to continue with the nortriptyline trial - but I just keep reading bad cardiac crap about the TCA's.

I think it is important to determine the probability of an untoward event, and not solely focus on its possibility.

Sure, AV block is a possibility, but just how probable is it? I don't have the answer to this question except to say that I have not yet seen it described on Psycho-Babble, and none of my doctors ever brought it up as an issue. I think it is critical to identify high-risk individuals, though. Is there any history of conduction abnormalities? The elderly should probably be screened for and monitored for such things, including the Brugada syndrome.

I hope nortriptyline comes to be your "magic pill".

;-)

It is going to necessitate a leap of faith on your part to view your elevated heart rate as a relatively benign side effect. Historically, I have seen my HR decrease from 120bpm to 80-90bpm with continued TCA use.

At the very least, I encourage you to use nortriptyline as a biological probe. As an experimental trial, you don't have to commit to taking the drug for the rest of your life. How much damage could it do if you were to take it for two months? If, during those two months, you experience a robust antidepressant effect, it might provide clues for you to use other agents polypharmaceutically to simulate the properties of nortriptyline.

I truly hope you find something that works for you, whatever that may mean.


- Scott

 

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