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Re: Is Anyone Succesfully Taking Tramadol Long-Term?

Posted by Brainbeard on July 26, 2009, at 10:23:07

In reply to Re: Is Anyone Succesfully Taking Tramadol Long-Term?, posted by SheilaC on July 26, 2009, at 9:27:32

> So, is there an antidepressant or antipsyochotic or other med that a doctor will prescribe that will give me the same effects that Tramadol will?
>
> I know I can't take Tramadol for depression and anxiety, but it does work. So what to take?

The chemically closest relative of tramadol is Effexor. The relief of the bladder thing must be an effect of noradrenaline reuptake inhibition (NRI). So if you would want to have both bladder relief and an antidepressant effect, you would have to take Effexor high dose, sinced only from higher doses (>75mg) does Effexor begin to really do some NRI. Effexor is infamous for its withdrawal syndrome too, though. And you'd get a lot more serotonin reuptake inhibition (SRI) than with just tramadol.

The bladder problem could be countered by any NRI, probably, say, reboxetine, or nortriptyline. An other AD could be added too that.

To have both qualities in one pill, you would have to look at the SNRIs: duloxetine (Cymbalta), milnacipran (Ixel), or the older, tricyclic SNRI imipramine (Tofranil). Tofranil seems to be a very effective SNRI, for me even in a low dose of just 25mg (it does boost my pulse quite a bit). It's a matter of mileage how much you'd need of any NRI for the bladder.


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URL: http://www.dr-bob.org/babble/20090721/msgs/908630.html