Posted by SLS on April 30, 2009, at 7:28:49
In reply to clonazepam, diazepam and paradox reactions, posted by sdb on April 30, 2009, at 3:48:54
> what I've heard is especially from clonazepam and to a lesser degree diazepam can cause paradoxical reactions. clonazepam seems to give a 'blue', bad feeling where anxiety or ocd like symptoms can be increased.
I wouldn't call the worsening of depression or OCD a "paradoxical" reaction in that it is not really opposite to the accepted therapeutic anxiolytic and hypnotic properties that they usually exert. A paradoxical reaction would be things like the emergence or worsening of anxiety or insomnia.
From personal experience and the accounts of others, clonazepam can indeed produce or worsen depression. It is usually a mild to moderate worsening. I have not heard of its potential to precipitate or worsen OCD. However, it seems that clonazepam has some poorly-understood serotonergic effects that indeed might be responsible for both psychiatric side effects.
- Scott
poster:SLS
thread:893537
URL: http://www.dr-bob.org/babble/20090426/msgs/893554.html