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Re: Buspar or Celexa for extreme GAD-Bleauberry » linkadge

Posted by bleauberry on April 13, 2009, at 17:08:31

In reply to Re: Buspar or Celexa for extreme GAD-Bleauberry, posted by linkadge on April 12, 2009, at 20:02:40

Yes I believe you are correct. To take it even further, I think the whole issue is more complicated than it looks. We only know a fraction of what these meds do. What I meant in general is that antidepressants tend to smooth out the peaks and valleys in cortisol curves, which is sometimes a good thing and sometimes not. And you are correct, it varies from one med to the other, and from person to person.

> I don't know if I'd agree with the notion that antidepressants will decrease cortisol.
>
> A number of studies suggest the SSRI's (esp fluoxetine and sertraline) increase cortisol.
>
> The only antidepressnats that have somewhat of a documented anti-cortisol effect are remeron and doxepine / amitriptyline. Some of the antipsychotics also decrease cortisol.
>
> Linkadge


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