Posted by desolationrower on March 17, 2009, at 2:57:15
In reply to Re: What medication should I try after all has fai » Girlnterrupted78, posted by metric on March 16, 2009, at 17:29:27
well, you don't seem to have tried a tca; wellbutrin sort of enhances norepinepherine, but i don't think its really comparably. i'd give one a go.
There are some similarities of valproate to nardil (in how they raise gaba levels), so since nardil didn't seem to work (hopefully you got up to a high dose?), i might hold off on that, it has some side effects, especially for girls; it is quite good for irritability, and can help anxiety.
I think clonidine/guanfacine are good medicines; they have pretty mild side effects, are cheap, and as long as a doc is open to suggestions, they aren't too hard to get. they can help with adhd symptoms, and tend to be more calming.
topiramate also has some evidence for social anxiety and controlling irritability. it can make you stupid, but it won't make you fat.
I agree it is frustrating when things stop working. One of my theories is that underlying poor health makes it less likely ADs will work; vitamin d3 and magnesium/zinc come to mind b/c of their interaction with the dopaminergic and nmda systems, respectively. it could be i focus on my health because its easier than fixing my head.
one thing - bruxism afaik is associated with hypersensitivity to dopamine. i think it also is more common in stage 1&2 sleep, so maybe a sleep drug would help, one that increased deep sleep. there was a report of gabapentin used to treat it.
it is frustrating when doctors seem reluctant to treat your condition
-d/r
poster:desolationrower
thread:884934
URL: http://www.dr-bob.org/babble/20090313/msgs/885735.html