Posted by sukarno on March 13, 2009, at 7:44:54
In reply to Re: In Defense of Cannabis, posted by Budzoid on March 12, 2009, at 22:40:23
I'm curious if anyone, especially Larry Hoover since he lives in Canada, has tried Sativex. Sativex is a prescription cannabis product made in Canada and sprayed either in the mouth or under the tongue. I assume this is absorbed through the mucous membranes of the mouth, thus bypassing the liver and avoiding the conversion from delta-9 THC to delta-11 THC.
Delta-11 THC is far more psychoactive and is generally regarded as unpleasant. That's why eating cannabis produces such strong effects compared to smoked/vaporized or sublingual preparations.
If you bypass the liver, it will go to the brain as delta-9 THC and give you the "high" (if you are seeking that) along with increased appetite, before it reaches the liver.
poster:sukarno
thread:877445
URL: http://www.dr-bob.org/babble/20090313/msgs/885145.html