Posted by SLS on February 19, 2009, at 13:25:20
In reply to Re: Prozac (fluoxtine) at 80mg....compared to other.., posted by rjlockhart04-08 on February 19, 2009, at 13:10:10
> Hi Scott
>
> Listen, i've been on the search bar, which has "massive" posts from 1999-now. About Prozac.
>
> Zoloft at a high dose causes Serotonin Saturation, which, means there is alot of serotonin in the synpase.
>
> My question, Prozac is Serotonin reptake, but also it uptakes indirectly NE, which maybe why it's considered "stimulating". It's not a stimulant, it only effects a nuerotransmitter that is activating (Norephephrine)
>
> Basically to get to the bottem...I take Dexedrine Spansules 4 15mg (2 at 9am) (2 at 3pm). Does prozac "blunt it's" effects by increasing serotonin levels, above dopamine levels?
>
> Cancelling it out...basically.
That's a great question. I don't know the answer for sure. However, my guess is that the Dexedrine might enhance the overall effects of the Prozac. I don't think there is any "cancelling out". Fluoxetine, but not other selective serotonin uptake inhibitors, increases norepinephrine and dopamine extracellular levels in prefrontal cortex. It might have something to do with its ability to block 5-HT2c receptors.
- Scott
poster:SLS
thread:881089
URL: http://www.dr-bob.org/babble/20090213/msgs/881106.html