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Re: nardil - blood sugar

Posted by SLS on February 7, 2009, at 6:27:54

In reply to nardil - blood sugar, posted by g_g_g_unit on February 7, 2009, at 6:09:48

Hi GGG_U

> sorry to add yet another nardil thread. i have been quite tolerant w/r/t to se's, yet this blood sugar issue is bothering me. basically, if i go more than an hour or two without eating something, i fall into a terrible hypoglycemic state, which it can take a while to recover from. i have brought this up to my doctor and he said he can't see how the nardil would be doing this, which is strange because pubmed returns numerous abstracts on how hydrazines affect glucose. i am following a low GI diet which helps with hunger somewhat, yet like i say, if i go without eating, the repercussions are pretty bad. is this a side-effect that most likely won't go away? now 2 days @ 60mg. feel really relaxed, almost to a point of sublime indifference, yet no other positive social benefits (i.e. talkativeness), no positive cognitive changes (still have brain fog, memory's terrible, etc.), incredibly tired during the day...

You'll need perhaps 3 weeks at 60mg if it is going to work at that dosage. Rule of thumb for Nardil dosage is 1mg of Nardil for every 1kg of body weight. I'll let you do the math. 1kg = 2.2 lbs. becomes xxx pounds divided by 2.2. A lot of people end up at 75mg.

Regarding blood sugar, Nardil (phenelzine) can make a mess of glucose/insulin dynamics. It has to do with glucose disposal rate produced by hypersecretion of insulin. Hypogylcemia is a documented side effect of Nardil. You already know that. I don't doubt that this is what is happening here. However, you might as well give this side effect time to mitigate. If not, there is always Parnate.

I actually developed hypoglycemia upon discontinuing Nardil 90mg. It just likes to play with insulin levels - either on the way up or the way down. It took about 2-3 weeks for my blood sugar to normalize.

It is disappointing when a doctor doesn't know everything but thinks he does, isn't it? It is a question of attitude.


- Scott

 

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