Posted by SLS on January 25, 2009, at 11:03:14
In reply to Seroquel - Why does it help so many conditions?, posted by SLS on January 25, 2009, at 10:54:32
* Correction:
> of particular interest, a 5-HT2c receptor antagonist. The _ANTAGONISM_ of this receptor is thought to increase norepinephrine and dopamine neurotransmission in the prefrontal cortex, which is thought to be involved in depression.
Normally when the 5-HT2c receptor is stimulated, it inhibits the release of dopamine and norepinephrine in the forebrain. When the receptor is blocked from doing its job, it allows for DA and NE neurotransmission to increase. This phenomenon is called "disinhibition".
Sorry for the error.
- Scott
poster:SLS
thread:876047
URL: http://www.dr-bob.org/babble/20090104/msgs/876050.html