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Re: Tianeptine and Agomelatine

Posted by Trotter on October 25, 2008, at 13:08:52

In reply to Re: Tianeptine and Agomelatine, posted by Trotter on October 21, 2008, at 22:03:27

Day 26 (on Tianeptine)

Had an awful day a couple of days back. In fact worst mood day in many months and there was no stressful event to trigger it. Anxiety, depression and brain fog. I was not suffering from anxiety prior to starting Tianeptine so this is certainly a side effect. Recovered somewhat the next day, but some anxiety still there.

Nearing the end of my fourth week. I keep daily mood ratings to chart my progress, and I can report that my average mood has been significantly lower in each of the four weeks (compared to average mood prior to starting). I think the factor which has caused this is the anxiety that didn't exist before. Most of the time this anxiety is subtle, but some days it is more dominant. This anxiety and emotional sensitivity, even slight paranoia, has also triggered depression. The most worrying thing about the anxiety is that it is not showing any signs of going away. In fact, if anything, it is probably worse in week 4 compared to week 1.

I have got to the point where I want to stop, but I am forcing myself to continue. If I stop now I will always wonder whether things might have improved if I had given it a bit longer.

Tianeptine reduces plasma serotonin, the opposite of SSRIs. Putting aside the awful side effects, I respond well to SSRIs. I am wondering whether people who respond to SSRIs have much chance on Tianeptine. One can argue that it could make things worse.

Trotter


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