Posted by bleauberry on September 9, 2008, at 17:44:36
In reply to Re: Brief immediate responses to meds?? - Advice Pls, posted by Four Feathers on September 8, 2008, at 22:57:54
> Given the above information, what would be your recommendation of other meds to try should my pdoc and I determine to discontinue Nardil? Would Nadolol be best for peripheral treatment or Pindolol as you mentioned (I am not very familiar with this BB). What about ADs to try at this point that would have a significant NE effect as this appears to be a major contributor in my case?
It is so hard, impossible actually, to predict based on mechanism what meds would work good or not. They are so much more complicated than the simple mechanics we talk about. I am not well versed on beta or alpha blockers so I can't offer input on that.
Since you have identified that norepinephrine is somehow a key player, that narrows the field of choices down a lot and should make it less confusing in pondering what direction to go. There are the TCAs nortriptyline or desipramine, with desipramine being the strongest on norepinephrine. Both come with a host of other side effects which spare a few people but are problematic for many. You could research those. Returning to Strattera is an option maybe? Unless you are feeling like you been there done that and want something different? I can understand that.
My favorite pick in the norepinephrine category is Milnacipran. Popular successful AD around the world, it hits norepinephrine compared to serotonin at about a 3:1 ratio. Though it is not a stimulant, it has a feel to it, in my opinion, that reminds me sort of in a way of ritalin. A beta blocker used with it in literature is Flomax, usually intended for prostate issues. For tricking the genes, case studies indicate success outcomes in combination with Risperdal or Zyprexa. In Japan Milnacipran is commonly combined with SSRIs.
For pure norepinephrine, there is Reboxetine.
For the mailorder meds such as Milnacipran or Reboxetine, a google search with the words buy and whatever med you want will give you some sources. Only a few sell Milnacipran and they are all reliable and dependable. Customs allows a 90 day personal supply without a prescription.
poster:bleauberry
thread:850938
URL: http://www.dr-bob.org/babble/20080903/msgs/851217.html