Posted by SLS on August 12, 2008, at 20:13:03
In reply to Asendin to replace Cymbalta?, posted by dmlvt on August 12, 2008, at 14:53:08
Amoxapine (Asendin) seems like a strange TCA to try first. It is a derivative of Loxapine, an old antipsychotic, and has been known to produce EPS.
I think it is worth trying at least one TCA. The two that have the mildest anticholinergic side effects are nortriptyline and desipramine. A drug that produces a high anticholinergic load can reduce the contractility of muscles. You won't be as strong or capable of completing as many repetitions as you are now. The differences are not dramatic, though.
There was some thought years ago that Asendin worked faster than the other TCAs. However, unless you have a psychotic depression, I don't think Asendin is the best match.
- Scott
poster:SLS
thread:845709
URL: http://www.dr-bob.org/babble/20080805/msgs/845788.html