Posted by blueboy on July 28, 2008, at 11:31:24
In reply to Full trial of Panate w/ no response?, posted by eric wagner on July 27, 2008, at 17:13:17
> I would like to know if anyone has used Parnate at an adequate dose for a full trial & never had a positive response
> Also, anyone who has aquired positive effects - how long did it take to notice them, & at what dose were you on?
>
> I have been on Parnate for approx. 5 weeks now
> I'm currently on 50 mgs./day (morning dose) & will increase it to 60 mgs./day at the end of the month
> I have yet to see any positive effects/lessening of symptoms as of yet
>I would say that this is not a "full trial". As long as you can tolerate the side effects, you should keep gradually upping the dosage, giving each dosage at least two weeks.
IMHO, after a five week titration period, the chances of successful response are fairly low. You may need to be *at* therapeutic dosage for ten days to two weeks before your mood brightens, and your therapeutic dosage could be significantly over 60mg/day. Unfortunately, the side effects normally start before the mood brightening.
The good things about MAOI's is that they have an extremely high success rate. The bad news is that the side effects are so nasty, a lot of people just can't tolerate them.
poster:blueboy
thread:842413
URL: http://www.dr-bob.org/babble/20080727/msgs/842571.html