Posted by okydoky on June 17, 2008, at 12:43:44
In reply to Re: does selegiline really mitigate DAergic cell l » okydoky, posted by SLS on June 15, 2008, at 5:21:26
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> It is the depression that is producing your dementia. It will resolve gradually as you respond to an antidepressant treatment robustly. The degree of dementia in depression is increased as one ages with the disorder inadequately treated. In fact, melancholy seems to be replaced by dementia in the elderly, thus the errant diagnoses of what is now known as depression-induced "pseudodementia". My personal opinion is that the hippocampus loses tissue volume as the result of atrophy due to a pathological reduction in its activation by efferent pathways. To compound matters, chronically elevated cortisol also results in the loss of hippocampal tissue volume.
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> Yes, the impairments in depression of cognition, concentration, and memory do indeed qualify for the use of the word "dementia" (not to be confused by the disease, Alzheimer's Dementia. "Dementia" is a generic term describing such functional impairments.
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> - ScottI wanted to thank you for the post. Got to it finally as I am further depressed and in a brain fog from taking Lyrica.
If I wanted to look for research about this would I look under "pseudodementia"?
oky
poster:okydoky
thread:834421
URL: http://www.dr-bob.org/babble/20080617/msgs/835060.html