Posted by undopaminergic on June 11, 2008, at 9:47:08
In reply to For undopaminergic Re: Restarting Parnate, posted by okydoky on June 7, 2008, at 9:38:10
> I posted somewhere my trouble with sleeping while on Parnate. I think you were the one that had a specific suggestion? I cannot find it.
>
> Do you recall this? Was it you or do you know what it was?
>Probably cyproheptadine (Periactin), because in addition to being a sedating antihistamine, it also blocks serotonin 5-HT2-receptors, which I suspect may be involved in MAOI-related insomnia. The same would apply to SSRI- or SNRI-associated insomnia. Cyproheptadine is also useful as an antidote to serotonin toxicity, so it may turn out particularly useful to keep around during MAOI-therapy.
poster:undopaminergic
thread:831304
URL: http://www.dr-bob.org/babble/20080606/msgs/834135.html