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Re: benzos and disinhibition

Posted by undopaminergic on May 7, 2008, at 16:31:22

In reply to benzos and disinhibition, posted by wishingstar on May 6, 2008, at 20:39:20

As others have suggested, the extended release (XR) version of Xanax may be a solution.

Zolpidem (Ambien), zopiclone (Imovane), and eszopiclone (Lunesta) are non-benzodiazepine hypnotics that may be less likely to cause disinhibition.

Melatonin may be worthy of consideration.

Cyproheptadine (Periactin) is a sedating antihistamine like diphenhydramine (Benadryl), but it has the additional feature of serotonin 5-HT2A-receptor antagonism, which may improve sleep quality.

A possible solution is to use a short-acting benzodiazepine such as triazolam (Halcion) or midazolam (Dormicum) to induce sleep, in combination with a sedating antihistamine to maintain sleep throughout the night. Since the effects of the benzo would dissipate before the morning, disinhibition would not result.


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