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SSRI's vs. TCA's

Posted by addinbc on April 14, 2008, at 20:06:24

Hi there;

Over the last 15 years, I have been on a myriad of antidepressants for anxiety/depression. These have maily only included the SSRI's (Zoloft, Luvox, Paxil, Celexa, low dose Effexor, etc...). Through all these trials, I have discovered that I am EXTREMELY sensitive to medications. (BTW - I can't tolerate Wellbutrin or Duloxetine, and Remeron made my mood worse - yuck!)

For me, these wretched SSRI drugs cause wretched side effects. They all cause extreme lethargy/fatigue ( i.e.; they make my body feel like lead - I am bedbound for the most part), major PAIN in my abdominal/diaphragm region, apathy, and they cut me off from 'myself'. After 15 years on these horrible drugs I am needless to say TIRED of living with these side effects. They basically make my life unlivable - I can't function while on them. Literally.

I've tried coming off them. After sorting through withdrawal effects, my anxiety/depression inevitably returns to such an extent that I have to go back on the drugs. Last time I tried to come off, I ended up in hospital for 6 weeks.

I feel SO trapped!! I cannot live with these drugs, but I can't seem to live without them either!!!

My doctor keeps saying to me that we are out of drugs to try. I assume he says that because he knows I'm sensitive to drugs and thinks that I likely would not be able to tolerate drugs in other classes (e.g. TCA's). Regardless, I find it very annoying!

I'm wondering if some people experience the TCA's as more tolerable than the SSRI's. I just can't stand these wretched drugs anymore!!

Any input would be most appreciated!
Thanks!


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