Psycho-Babble Medication | about biological treatments | Framed
This thread | Show all | Post follow-up | Start new thread | List of forums | Search | FAQ

Re: Why I would not consider taking Deplin

Posted by Darwin on January 29, 2008, at 16:16:22

In reply to Re: Why I would not consider taking Deplin, posted by Abby Cunningham on January 29, 2008, at 13:49:26

> also see # 3.
>
> Here is the info from the drug company's web site:
>
> 1. Folic acid is a man-made product that needs to be broken down through a lengthy 4-step process. Folate that comes from your diet (e.g. green vegetables) needs to undergo a 3-step transformation. Deplin® is able to be used immediately upon absorption.
> 2. One Deplin® 7.5mg tablet is bioequivalent to taking fifty-three 1,000 mcg folic acid tablets every day.
> 3. Deplin® is unaffected by a common genetic polymorphism that compromises the breakdown of folic acid into L-methylfolate. This polymorphism is common in over half of the general population.
>

Actually, this is a bit misleading. Although taking 53 1,000 mcg folic acid tablets may result in 7.5 mg of l-methylfolate (one Deplin tablet) the opposite is not true ... l-methylfolate is not converted to folic acid. So, you could take 1000 Deplin tables yet not 1 mg of folic acid would be produced. This is significant because folic acid and l-methylfolate have different effects and it could be that the increased colon cancer rates are due to folic acid and not l-methylfolate.


Share
Tweet  

Thread

 

Post a new follow-up

Your message only Include above post


Notify the administrators

They will then review this post with the posting guidelines in mind.

To contact them about something other than this post, please use this form instead.

 

Start a new thread

 
Google
dr-bob.org www
Search options and examples
[amazon] for
in

This thread | Show all | Post follow-up | Start new thread | FAQ
Psycho-Babble Medication | Framed

poster:Darwin thread:809519
URL: http://www.dr-bob.org/babble/20080124/msgs/809584.html