Posted by ny2bk on January 8, 2008, at 19:52:18
In reply to Phenelzine vs Tranylcypromine (Nardil vs. Parnate), posted by Phoenix1 on January 8, 2008, at 12:31:27
> I'm wondering if anyone can share their objective/subjective observations on Nardil vs. Parnate. I'm on Nardil. I'm just doing some reading and it appears that Parnate is preferred. Fewer side effects, less toxicity, similar efficacy. I think I/my pdoc chose Nardil because it is more anxiolytic than Parnate but now I'm questioning the decision. Please share your thoughts on the differences between these two especially if you've tried them both.
>
> Phoenix1First let me say parnate was also reformulated from a sugar coated pill to a dry film like one.Supposedly this holds no differance to the drug,however having used both,i definatly find the sugar coated non u.s version to be a reminder of how much better parnate ONCE WAS HERE.
On that note,the basics are,
Parnate initialy stimulating for some,works fast regardless in terms of effect.Parnate is both sedating and fatique causing,so its not a clear stimulant,theres no onset rush or crash like a ampehtamine.
Parnate also is good at if not lifting a mood in turn rather taking away the gut fear in depression,it sorta seems like a mood stablizer at times where if depression was fear driven,bed ridden parnate kinda crushes that and makes u kinda EH to it and able to live life.
It for me increases libido highly,very highly,however causes a extreme difficulity in orgasim.Almost an impossability at times.
Parnate also has a less accumative effect,almost as if you start the drug over from scratch every day,which gives it a scary "hard drug" feel opposed from a more therputic one.
Last i found parnate to actualy play well with many secondary meds,i.e benzos,mood stablizers,even stimulants in attempt to enhance it or stop its tolerance.
Nardil has a notorious weight gain issue,and decrease in sex drive.Unlike parnate nardil doesent have the quick onset of action,HOWEVER nardil once felt,seems to have a more solid back bone...its almost funny how the two resemble xanax to klonopins differances.
Nardil has a more potent social effect as well,however many meds can be added to parnate to attempt to come close to nardils.In my opinion id use parnate if i were bed ridden and in a dangerous time of depression,parnate will come on faster when you dont have much time to hang on and wait.
Nardil i would use for a more stable med,when your not in immediate need for reliaf and can wait a while for the drug to kick in.Nardil will be more accumative and more solid.
A few notes to be made is nardil as stated by a community of users or ex users was a almost different med pre formulation change.This is just a quick drift,however the differances of the two can be much more detailed.
poster:ny2bk
thread:805096
URL: http://www.dr-bob.org/babble/20080105/msgs/805197.html