Posted by clipper40 on November 29, 2007, at 6:55:42
In reply to Re: Trivastal is an a2-adrenoreceptor antagonist?, posted by linkadge on November 28, 2007, at 19:13:30
> the a2 receptors are inhibitory autoreceptors.
> They are invovled in homeostatic control over norepinephrine release. When you block these receptors it results in a *release* of norepinephrine. When you activate these receptors (like clonidine an alpha-2 agonist) you get less norepinephrine release.
>
> So drugs like mirtazapine, trivestal, or yohimbine, alpha-2 antagonists, will cause norepinephrine release.
>
> LinkadgeThanks. That was my other thought that maybe these were autoreceptors. There's no way to tell that from their name though. I guess you just have to know that...but now I do.
C40
poster:clipper40
thread:797501
URL: http://www.dr-bob.org/babble/20071125/msgs/797563.html