Posted by JayBTV2 on November 27, 2007, at 7:16:28
Hello,
I've been taking Lamictal (200mg) with Depakote ER (250mg). I ran out of the Depakote ER and have a ton of the Immediate release remaining. I figured I would just half the immediate release and be OK.
Now I know Depakote almost doubles the half life of Lamictal. This apparently takes place at around 250mg of Depakote. What I'm wondering is if the ER (since it's released slowly) would have less of a doubling effect than the Immediate Release?
I'm asking because since yesterday (my first day on IR) I've had cold like symptoms (bit of a sore throat yesterday/cough today). I just recently (3 weeks ago) got over a bad cold so I find it hard to believe I could have picked up another virus. Perhaps that is the case.
Either way I'm wondering if perhaps my change to Depakote IR caused a sudden increase in my Lamictal levels. I have heard of people getting flu like symptoms when increasing Lamictal so I'm thinking maybe that's what happened.
The sad thing is I'm going to visit my girlfriend on Thursday and I really don't want to be sick on that trip. So in some ways I'm kinda hoping the med change might be responsible for my current symptoms. I cut back a bit on the depakote this morning to see if that helps at all.
I know I should talk to my doctor but It'd be difficult to get in to see him in the next couple days.
Thanks for any insight!
-Jay
poster:JayBTV2
thread:797271
URL: http://www.dr-bob.org/babble/20071125/msgs/797271.html