Posted by Brutus1 on March 19, 2007, at 18:37:18
In reply to Re: Mode of action, MPH (Ritalin) and Buproprion., posted by med_empowered on March 19, 2007, at 15:30:41
Thanks. Some beleive MPH might also hit the H1 (Serotonin) receptors downstream also? Do you still take Dex?
B
> Wellbutrin is pretty stimulant-ish (its like a mild version of Tenuate), but I think there differences. For one, b/c of the reuptake inhibition, wellbutrin reduces dopamine release, which is something a lot of ADs do. This is also why you can sometimes combine it with antipsychotics w/ good results. MPH does reuptake inhibition but, as far as I know, doesn't have any major impact on dopamine release. Its also sometimes used in schizophrenia, with stable patients with a lot of negative symptoms, or stable patients mired in drug-induced sedation (like with clozapine).
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poster:Brutus1
thread:742117
URL: http://www.dr-bob.org/babble/20070314/msgs/742246.html