Posted by laima on February 25, 2007, at 23:14:08
In reply to Drug manufacturing and quality control, posted by Squiggles on February 25, 2007, at 17:21:34
Yes, a little- my doctor consults on some drug trials and had much to say about how the fda holds generics to much lower level of scrutiny than brand name. Generics also are officially allowed to take certain measures to reduce their costs: ie, use different quality or amount of raw ingredients, and are not subjected to loads of tests and inspections. He didn't blink an eye or utter any disagreement at all when I suggested brand and generic adderall are not the same. Rather- "There could be many reasons contributing to that...many patients feel the same..." I wrote about it in one of my adderall threads. Apparently, fda is stretched thin, and more concerned with establishing safety or efficacy of new drugs, and slacks off considerably with generics. Sounds like as long as they are in the ballpark and the factory is sanitary- they are good to go. A couple months ago there was a thread here on babble about how generics are allowed by law a 20% give or take in difference from brand name. Pharmacists love to deny this, but personal experience begs to differ, and I'm thrilled that my doctor not only didn't deny it, but offered explanaitions.Think- fda can't even keep track of spinach or peanut butter quality!
> Does anyone know about the possible variability of quality control in drugs?
>
> Maybe this is the reason 300mg imipramine is required and is still weak (not my case).
>
> thanks for any tips you may have;
>
> Squiggles
poster:laima
thread:735309
URL: http://www.dr-bob.org/babble/20070224/msgs/736287.html