Posted by SLS on January 15, 2007, at 21:20:42
In reply to Re: Can Someone Explain Providgil So many Differen » SLS, posted by blueberry1 on January 15, 2007, at 16:20:15
Hi Blueberry.
> Yeah I think the general understanding of Provigil is it increases glutamate release.
>
> I wonder though, what do you think? I do not know anything about it, but I have read many times about 'glutamate toxicity'. I wonder if Provigil in the longrun does some brain damage? I wonder if Provigil users should be using high doses of anti-oxidants? Or a benzo along with it? Or no concern at all? What are your thoughts?I'm afraid I don't have any. :-)
Certainly, excessive glutamatergic activity can produce neurotoxicity via calcium influx. However, I don't know the specifics of how Provigil works to know if this is somehow prevented. So far, I have not seen any concern raised in the medical literature.
- Scott
poster:SLS
thread:722202
URL: http://www.dr-bob.org/babble/20070113/msgs/722725.html