MAO-a inhibiton from EMSAM, tyramine metabolism

Posted by psychobot5000 on January 14, 2007, at 15:55:36

In reply to Re: ENSAM Question, posted by SLS on January 14, 2007, at 11:48:44

> Perhaps the pressor response is dependent upon inhibition of gut MAO and not brain MAO?
>
> - Scott
From what I've been told, that is quite correct. If I remember right, a 6mg EMSAM, worn all day, will produce MAO-a inhibition of 70% or more, and above 90% of MAO-b. Yet, there is enough MAO-A left in the gut to prevent a pressor crisis. It's important to remember that blood levels of of selegiline from the patch are much higher than with tablets, so you get dual inhibition at all doses.

Thread

ENSAM Question blueberry1 1/13/07
Re: ENSAM Question SLS 1/13/07
Re: ENSAM Question SLS 1/13/07
Re: ENSAM Question halcyondaze 1/14/07
Re: ENSAM Question SLS 1/14/07
MAO-a inhibiton from EMSAM, tyramine metabolism psychobot5000 1/14/07

Post a new follow-up

[722257]

Notify the administrators

Start a new thread

poster:psychobot5000 thread:721900
URL: http://www.dr-bob.org/babble/20070113/msgs/722257.html

	for
in