Posted by Quintal on January 12, 2007, at 14:03:47
In reply to People who know about Parnate - talk to me.., posted by Jimmyboy on January 12, 2007, at 11:15:13
>1. I am currently taking Serzone, how long do I have to go between stopping Serzone and starting Parnate?
Official advice is to wait one week between stopping Serzone and starting Parnate.
>2. What is the starting dose, what is a good schedule of how to raise the dosage.
The starting dose is usually 20mg; one in the morning and one in the afternoon, 3:00PM at the latest. The dose is then usually raised to 30mg (10mg in the morning and 20mg in the afternoon [though some recommend the reverse if insomnia is a problem]) if no response after two weeks.
>3. How long for it to start working?
Similar to other AD's up to a month, but the stimulant effects may appear straight away. I felt the antidepressant effect in the first week.
>4. How bad are sexual side effects, compared with SSRI's?
Parnate rarely causes severe sexual side effects. Many people (myself included) find it has a mild aphrodisiac effect at first. Ejaculation might be slightly delayed if you have sex before the stimulant effect of the last dose wears off but the sex is still pleasurable unlike the SSRI numbness.
I like Parnate. I felt euphoric when I raised the dose to the 80-120mg range, but I was also taking it with ~4mg Klonopin which might have helped smooth the jitters. Low doses (20-30mg) made me feel more anxious and depressed. I recommend you give Parnate a try so long as you have access to benzos or other sleeping tablets in case you need them (you probably will). I found that when the stimulant effect of Parnate wore off the sedative effect of the Klonopin took over and I fell into a deep sleep but I needed to take another 10mg dose in the afternoon (about 5:00PM) to avoid the notorious afternoon slump and keep me going until bedtime.
Q
poster:Quintal
thread:721622
URL: http://www.dr-bob.org/babble/20070107/msgs/721692.html