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Graph comparing Lamictal brand to new UK generic

Posted by ed_uk on January 7, 2007, at 13:29:05

In reply to Re: chiral molecules?, posted by naughtypuppy on January 7, 2007, at 10:58:18

Hi

As an example, here is a graph which was produced when determining whether Dr. Reddy's lamotrigine generic was bioequivalent to the original brand: Lamictal..........

http://www.mhra.gov.uk/home/idcplg?IdcService=GET_FILE&dID=25158&noSaveAs=0&Rendition=WEB

Open the link and scroll down to page 14.

The x-axis shows time. The y-axis shows the drug level in the blood.

As you can see, the two formulations are very close. Dr. Reddy's generic appears to produce very slightly higher blood levels than Lamictal, but this may just be due to chance.

Ed


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poster:ed_uk thread:719885
URL: http://www.dr-bob.org/babble/20070107/msgs/720186.html