Posted by SLS on January 3, 2007, at 15:38:41
In reply to Re: Has anyone here had a remssion for long? » SLS, posted by tensor on January 3, 2007, at 9:13:34
> I discontinued Lamictal a few weeks ago because it was making me so tired and I had no response from it. First I took it with nortriptyline+Remeron and later with Zoloft+Remeron. I tried this for several months, but nothing. Nortrip+Rem was the combo I last crashed on, about five-six months ago. So I abandoned Lamictal before Wellbutrin, so to speak.
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> >I would be most interested to see how Remeron + Wellbutrin works out for you.
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> Yes, I agree. But maybe I could keep Zoloft in my regime for a while. That would be 15mg Remeron + 300mg Wellbutrin and 50mg of Zoloft.
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> >What has been your experience with tricyclics and MAOIs?
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> No MAOIs, I have tried nortrip and clomipramine, I have responded to both. I tried clomipramine years ago but quit in quest for a med with better aim, it has a pretty disturbing s/e profile.
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> For me the dopaminergic effect of Lamictal was transitory, lasted a few days after each dose increase. Speaking of Stahl, MD. He recommends adding Remeron to Wellbutrin for residual depressive symptoms. Anyway, I could just add 15mg of Remeron to my existing combo and see what happens, I can always ditch Zoloft later, what do you think?It sounds like a reasonable plan to me. I'm sorry the Lamictal didn't help more consistently. Yours is not an unusual story, though. As far as the tiredness is concerned, I don't know if it is a prognosticator of poor response or not. I guess it would have been nice to see what Lamictal + Wellbutrin would have done.
You've been on a lot of stuff. It is easy to conclude that nothing will ever work, except that you know that something already has. You might be a responder to a triple-uptake inhibitor with or without Wellbutrin. These drugs are still a few years away. In the meantime, you can try to construct the best response possible to use as a bridge until some of these newer treatments come to market. You know, it is too bad that we will probably never see another SSRI or SNRI developed for clinical use. There are people who achieve remission on one SSRI and not another. The same seems to be true of Effexor versus Cymbalta. I don't see how it hurts to have a few more weapons available in the armamentarium. It is like the advantages conferred upon the community to having a plethora of available antibiotics. Of course, one can debate the possible overuse of both antidepressants and antibiotics, but that is a separate question.
At what point would you consider an MAOI?
- Scott
poster:SLS
thread:718547
URL: http://www.dr-bob.org/babble/20070101/msgs/718951.html