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Re: Seroquel for sleep - doesn't work » ronaldo

Posted by yxibow on October 7, 2006, at 4:52:37

In reply to Re: Seroquel for sleep - doesn't work, posted by ronaldo on October 7, 2006, at 3:03:09

> > My Daughter takes 50mg and wakes in fours hours too. Does anyone know the longivity of a dose? Love Phillipa
>
> According to this chart http://sl.schofield3.home.att.net/medicine/psychiatric_drugs_chart.html
> Seroquel only has a half life of SIX HOURS. That might explain why after taking it at 9.30 pm and going to sleep at 11.00 pm I am awake again at 4.00 am or 5.00 am. Should I take some more at that point?
>
> Thanks to prodgirl for the link to the chart.


No, actually most people who take Seroquel as a neuroleptic take it once at night because it has HUGE effects at H1, and for those who have schizophreniform or bipolar (which I dont) disorders, the profile is almost usually, but not always sufficient for once daily. Trust me, 800mg at night and I'm out.

The Lithium may be creating a hyper-insomnia situation, I wouldn't be surprised. You might need a larger dose if you're considering Seroquel as a sleep agent, although at that point it is exhibiting a serotonergic profile.

Have you tried Ambien at 20mg or Lunesta at 3-4mg ?

 

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