Posted by circusboy on July 16, 2006, at 19:55:59
In reply to Weepy, not sure what's going on, WB? Buspar?, posted by Racer on July 16, 2006, at 10:16:50
Heya Racer,
I don't have anything to add from my own experience, except to say that I'm going through a similar sort of thing right now with Strattera. I hate that you lose track of yourself so much on these psych drugs...
Anyway, if I were to play amateur psychopharmacologist, I'd say I was suspicious of BuSpar's dopamine-D2 receptor antagonism. As you probably know, antipsychotics work through this mechanism, and they're known to induce "negative" symptoms (including depression) even as they help with the nasty psychosis. Of course, most of them do a lot of other unhelpful stuff as well (like muscarinic and adrenergic blockade), so maybe it's not the D2 antagonism that does it.
A little knowledge can be dangerous. :) Anyone else?
I really hope someone can help you, or that this awfulness somehow resolves on its own. It's hard not to obsess over the subtle and not-so-subtle psychological changes these drugs cause, but doing it diverts so much energy. I struggle with this all the time.
-cb
poster:circusboy
thread:667471
URL: http://www.dr-bob.org/babble/20060709/msgs/667583.html