Posted by willyee on May 30, 2006, at 12:44:47
In reply to My Parnate Experience...what went wrong?, posted by Crazy Horse on May 30, 2006, at 11:22:57
Well just fyi i can relate to everyone of ur problems,in fact they are mine as well.
However the options available are so slim im terrifeied at the thought of being off parnate and not having something to help.
But i would definatly say its time for me as well to get off.Im working on a way.
BTW whoever tells u parnate insomnia goes away is totaly not famialiar enough,it surly doesent,its simply the actions of the drug,and it doesent disappear,it seems docs love to say this when any complain of a side effect is laid a there feet,oh it will pass.geez
Also i as well disagree with most of those studies on pub med i believe.....
1.Parnate with the addition of a stimulant......Wellbutrin.--- I found this just made me feel simply yucky,totaly dispruted parnates normal effects,and add absolutly no benifit.
2.Parnate with the addition of Amphemaines....-----Parnate with a ritalin combo,at first seemed ok,more energy,then in a matter of a day or so,it reversed,i was experiancing more fatigue,however my body was tired and weak but there was a certain part of my brain that seemed light and i could not sleep,it was very very annoying.
Also this combo put me in ER,i becaome maniac,at my pc for 2 days straight,dident shower,eat or anything,and i did not notice,until of course it was so obvious it was too late,i began haclunitaing falling in and out of min sleep patterns not knowing if i were in a dream or not,lets not forget either this combo in the literarature says this should be done under CLOSE supervision and for truly treatment resiseant,i simply dont see it as a option.
3.Parnate at high doses.
--- This is tricky,sometimes all that would help is a higher dose as in 50 maybe 60 mg,it feels like an aspirin to a headache.
HOWEVER i dont believe it is benificial on a everday basis,this is day three for me,the first day was good,second good,this morning i did everything the same,sleep last night,morning activities etc.......and that dose of parnate is very strong,im sweating,i fell internal shaking and knowing the drug well i feel simply as if i took too much,simple as that,and the dose is the same.
So that whole entire data about parnate combos,i hold little value to it,i mean its based on an extremly SMALL study,and there are also studies on headweb that showed the addition of stimulants to parnate did NOT offer addiotnal benifit.
What i personaly find is u cant just augment parnate with a single agent,as it behaves differently,at least for me.Now some succesful augmentors i have had with parnate ill share,
1.Klonopin of course,and xanax,however not all the time but in certain times absolutly.2.L -theanine --- nothing dramatic,however in addition to parnate,has shown in times to be very helpful.
3.Kava kava--- i have given up on it now,after many many attmepts,but when kava was more readly avaiable it too at times worked great in addition to parnate.
4.Caffine..... caffiene in the form of the pill,not soda has many times offered a subtle lift to a parnate dose,but again this was certain times,where other times it caused agittation.5.Xyrem/ghb same as l-theanine in combo with a benzo at times has worked GREAT!
6.Lopressor.... a beta blocker,again nothing dramtic but many times has helped in a small degree that was well wworth it.
7.L-dperenyl liquid........ at times offered a kinda kick start to parnate,however its a very serious combo.8.Taurine......simple over the counter taurine in combo with a benzo again has helped.
So finaly ill say this,probualy the best combo i have found using parnate is as follows.
30---40 mg parnate
.25--.5mg of klonopin
Partial tab of -theanine-cap opened and poured into war water.
---a few droplets of xyrem,prob 500 mg to 1 gram max.
Let this settle over a time frame of at least an hour,then judge how u feel,at this point if there is excess stimulation best thing is additonal klonopin in very small amounts.
If sedation the small portions of a caffine tab work.Here it seems as if ur basicaly trying to balance the main neuros,since the substances mention hit all of them somehow,i know it sounds like a lot,but actualy all of the stuff i mentioned,l theanine etc are mostly neuro protective and pretty safe.
The brain is so complex,i dont see how a single pill with a single action will ever work,mainly because raisng chemicals in the brain only lead to both rebound and imbalinces of other chemicals,this is just a fact.
Sorry for the long post.
poster:willyee
thread:650434
URL: http://www.dr-bob.org/babble/20060530/msgs/650465.html