Posted by linkadge on March 23, 2006, at 9:07:23
In reply to Re: A very interesting article re: SSRI long term use, posted by Meri-Tuuli on March 23, 2006, at 5:19:31
yeah, I liked the lines:
The treatment of depression with SSRIs essentially may create a functional imbalance of the primary monoamine neurotransmitters with serotonin excess and norepinephrine or dopamine deficiency. Stimulation of serotonin (5-HT2A) receptors in the mesocortical centers may reduce dopamine activity there and cause apathy and decreased libido.7 Serotonin excess may suppress norepinephrine and dopamine activity in other pathways, which may explain why asthenia and its related symptoms of apathy and amotivation are commonly seen as residual symptoms of depression in long-term treatment and as the most common features of antidepressant tachyphylaxis. Treatment of an anxious, depressed patient with an SSRI commonly results in a fatigued, emotionally flat person who still suffers some of the disability associated with depression.
poster:linkadge
thread:623575
URL: http://www.dr-bob.org/babble/20060322/msgs/623597.html