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Re: mice raised on prozac grow up depressed » linkadge

Posted by SLS on October 24, 2005, at 5:55:18

In reply to mice raised on prozac grow up depressed, posted by linkadge on October 23, 2005, at 13:15:58

> http://mentalhealth.about.com/b/a/121991.htm

I haven't tried to find the actual publication or abstract, but there is too little described in this review to evaluate what's going on with these mice. Were there sham treatments given as a control? Hopefully. What was the dosage of fluoxetine given to these mice? Unknown.

It sounds sort of like PTSD to me. I think these mice might have been traumatized and behaviorally altered by regular injections of supratherapeutic dosages of an anxiogenic drug. This would not be extrapolatable to how people are exposed to this drug. That said, it is difficult to believe that any psychoactive drug will not produce some significant changes in a rapidly developing brain.


- Scott

 

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URL: http://www.dr-bob.org/babble/20051024/msgs/571271.html