Posted by Laurie Beth on October 19, 2005, at 8:26:46
In reply to Does Zoloft Effect Dopamine at all?????, posted by Ryan2828 on October 19, 2005, at 6:34:11
I had severe difficulty in focusing (and remembering and feeling and doing anything at all) after several years on high-dose (200-300 mg) Zoloft. My pdoc was recommending I switch to Effexor, presumably because of the noradrenalgic effect. After research led me to conclude that there was not much more reason to hope that Effexor would be better than Zoloft, so I decided to just go off Zoloft and see what that is like. I've been SSRI-free for almost 2 months now. I'm not sure yet what the result will be. So far, it seems like I'm feeling more, better able to concentrate, and more energetic ... at least for the part of the month ... also more irritable, though. But it's only be two months.
They say Zoloft is supposed to have some positive effect on dopamine, but from my experience, long-term, high-dose Zoloft may have decreased my dopamine.
poster:Laurie Beth
thread:568780
URL: http://www.dr-bob.org/babble/20051017/msgs/568798.html