Posted by SLS on September 21, 2005, at 7:55:27
In reply to Cymbalta Does Not Seem To Work Compared To Effexor, posted by TommyIsland on September 21, 2005, at 1:14:23
I echo M_E's question regarding the motivation for the switch.
How high did you go with the Effexor? If tolerated, anything less than 300mg would not represent an adequate dosage for a trial.
How much Cymbalta are you taking?
Many people react to Cymbalta the way you describe. Others find it to be "cleaner" than Effexor. You obviously find it worse than Effexor. The choosing of treatment is little more than trial-and-error. If the amotivation and fatigue are drug-induced and have persisted for two months at a steady dosage, they probably will not disappear.
Given your partial antidepressant responses to both Effexor and Cymbalta, you might want to move on to a tricyclic. Should it be necessary, you could add back the Effexor. I like the combination of Effexor + nortripyline.
Have you tried Wellbutrin in combination with Effexor?
Can you describe in more detail what you mean by "rollercoaster"?
- Scott
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> I was on Effexor XR for over 5 years and it was a rollercoaster of a ride. The bottom line was that it seemed to work a lot better than Cymbalta. My doc recently switched me to Cymbalta about 2 months ago and it has been nothing but pure hell. My motivation factor is non existant and to take a shower seems like the biggest chore in the world. My moods go up and down almost minute by minute. My appetite is very low and my energy levels are non existent. Has anybody else experienced any of these symptoms while taking Cymbalta and has anybody else been on Effexor XR prior to taking Cymbalta? Please let me know where to go with this. I'm thinking of immediately switching back to Effexor XR.......
>
> Tommy!!!!!!!!!!!
poster:SLS
thread:557557
URL: http://www.dr-bob.org/babble/20050921/msgs/557615.html