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s/s serotonin variant more depressed responds less

Posted by linkadge on August 30, 2005, at 17:27:04

I have been reading on the variants of the gene that encodes for the serotonin tranporter.

It seems that people with the s/s variant of the gene have a higher lifetime level of depressive episodes and depressive responces to traumatic events.

But get this. The people with this variant don't respond well to SSRI's. Which makes sence since they already have a slow reputake of serotonin.

According to a few studies, people with the short variants of the serotonin gene respond poorly to antidepressant medication.

Perhaps tianeptine would offer more hope for people with the s/s varient of the serotonin transporter gene?


Linkadge



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poster:linkadge thread:548837
URL: http://www.dr-bob.org/babble/20050827/msgs/548837.html